Comparison of the Immunosuppressive Effects of Dexamethasone, Flunixin Meglumine and Meloxicam on the In Vitro Response of Calf Peripheral Blood Mononuclear Cells

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Comparison of the immunosuppressive effects of dexamethasone, flunixin meglumine and meloxicam on the in vitro response of calf peripheral blood mononuclear cells.

This study compared the immunosuppressive effects of dexamethasone (DEX), flunixin meglumine (FLU) and meloxicam (MEL) on the peripheral blood mononuclear cells (PBMCs) of seven healthy Holstein calves in vitro. DEX significantly inhibited lymphocyte proliferation and expression of interferon (IFN)-γ, interleukin (IL)-2 and IL-4 messenger RNA (mRNA) in comparison with FLU and MEL. FLU and MEL d...

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ژورنال

عنوان ژورنال: Journal of Veterinary Medical Science

سال: 2011

ISSN: 0916-7250,1347-7439

DOI: 10.1292/jvms.10-0422